There are various main characters. Some are the tough survivors who have been through a lot, like Rick. He is often a central figure in many stories, using his leadership skills to keep the group alive. Another could be Michonne, a fierce fighter with her katana, who brings a sense of security to the group.
In some of the short stories, there might be plots centered around the discovery of new weapons or defenses against the zombies. Maybe a character stumbles upon an old military bunker with advanced weaponry. But then they have to figure out how to use it without attracting more zombies, and also deal with other groups who might want to take it from them.
The story of Negan is also a top one. His brutal rule over the Saviors and his complex relationship with other groups, especially his interactions with Rick's group, made him a very interesting character in the series. He brought a new level of danger and unpredictability to the post - apocalyptic world of 'The Walking Dead'.
Michonne does die in the comics. The circumstances surrounding her death were quite dramatic and had a significant impact on the story's progression. It happened during a major conflict with other characters.