In addition to the obvious ones like Naruto and Sakura, other characters from Sasuke's clan might interact with him. For instance, if there are any remaining Uchiha members, they might have mixed reactions. Some could be shocked and try to figure out what happened, while others might be more accepting. Also, characters like Shikamaru, who is very observant, would surely notice the change in Sasuke and might have some unique interactions, perhaps trying to figure out how this change could affect their team dynamics or the overall situation in the village.
Well, perhaps a plotline could involve Sasuke turning into a girl and using this new form to his advantage in some undercover mission. He could infiltrate an enemy group more easily as a girl. Also, there could be a love triangle where some of the characters who previously saw Sasuke as a male now have different feelings towards him as a girl, which would create a lot of drama and conflict.
His character development would likely be more focused on emotional aspects. As a girl, he might be more in touch with his feelings and less likely to bottle them up. For example, instead of being so stoic all the time, he could show more vulnerability.
One possible plot could be that Naruto turns into a girl to infiltrate an all - female organization that is suspected of having ties to a new threat. As a girl, he has to deal with the different social dynamics among the women, like cattiness in some cases but also strong sisterly bonds. He also has to hide his true identity while trying to gather information.
A common theme is identity crisis. Sasuke suddenly being a girl would make him/her question who they are now. Another theme could be acceptance, both from Sasuke herself and from the other characters. Also, there might be a theme of newfound friendship. As a girl, Sasuke might make new friends that he wouldn't have made before.
There could also be new characters introduced in the fanfiction. Maybe a female wizard who befriends Harry in his new form and helps him understand the female side of the wizarding world better. Or perhaps a villain who specifically targets Harry because of his unique transformation, seeing it as a weakness to be exploited.
One interesting plot could be that as a girl, Harry has to navigate the different social dynamics in Hogwarts. For example, he might be treated differently by his male friends who now see him as a girl. They could be more protective or act a bit awkward around him.
She could also change in how she approaches relationships. Before, as a boy, Sasuke was more reserved in his interactions with others, especially with Naruto. But as a girl, she might be more forward in expressing her feelings towards Naruto, whether it's friendship or something more. This could lead to some really interesting character development arcs and new plot directions in the fanfiction.
For Naruto, he might become more protective of Sasuke as a girl. Their friendship could take on a different dynamic, with Naruto being more chivalrous perhaps. Sakura might initially be jealous but then they could form a stronger bond as girls sharing common experiences. Kakashi would probably have to adjust his mentoring style to account for Sasuke's new situation.
Well, a possible plot could be Sasuke's transformation into a girl is part of a powerful jutsu gone wrong. As a girl, she has to find a way to reverse it. In this process, she might discover new aspects of her own abilities or weaknesses. Also, there could be a plot where she has to prove herself in battles all over again, since some might underestimate her as a girl.