The 'profundis novel' could potentially cover a wide range of topics. It might be a story of self - discovery where the protagonist ventures into the profundis of their own identity. It could also be about exploring the deeper meaning of life, love, or death. Without more information, it's difficult to say exactly what it's about, but it's likely to contain elements that are deep - seated, thought - provoking, and perhaps a bit mysterious.
Maybe it has a really distinct setting. For example, if it's set in a world that's a blend of different cultures or has some unique magic system, that would set it apart. Also, the characters could be very well - developed, with complex personalities and motives that draw readers in. It could also have a plot that's full of twists and turns, which is always exciting in a manhwa or novel.
Since I don't know much about 'profundis manhwa novel', it's hard to give an exact match. However, if it has a dark or mysterious theme, 'Bastard' could be something to look into. It has a really gripping and somewhat disturbing plot that keeps readers on their toes. There are also manhwas like 'UnOrdinary' which deals with power dynamics and has a large following.
The cartoon of a sick woman and children might symbolize the need for better healthcare or draw attention to the struggles faced by those in poor health. It could also be a form of artistic expression to evoke empathy and awareness.