Sure. Itachi's saving of Sasuke was a crucial moment in the manga. It was tied to his hidden motives and sacrifices for the greater good of the ninja world and Sasuke's future.
In this kind of fanfiction, Itachi might use his powerful Sharingan abilities. He could perhaps create illusions to mislead Orochimaru and his minions, then quickly snatch Sasuke away. For example, he could make Orochimaru think that Sasuke is in a completely different location while he secretly approaches and rescues him.
Sasuke would likely become more protective. Usually Sasuke is very focused on revenge and his own power, but when faced with baby Itachi, he would feel the need to shield him from all harm. His cold exterior might soften a bit as he looks at the innocence of baby Itachi.
Their relationship could become more complex. On one hand, they have achieved their goal together, but on the other, Sasuke might feel guilty for killing his brother with Naruto's help. Naruto, in turn, might worry that Sasuke will go back to his old ways. So, while they have this new connection, there could also be new tensions and insecurities in their relationship.
Well, in the fanfiction, a likely plot development is that Naruto's newfound power, perhaps a unique form of Rasengan, is crucial in the fight against Itachi. Sasuke, on the other hand, is initially blinded by revenge but Naruto helps him see that there's more to Itachi's actions. This could lead to a situation where they don't actually kill Itachi but rather free him from whatever binds him to his 'evil' deeds. The fanfic might then explore how they deal with the consequences of not following through with the kill.
Sakura may initially be paralyzed by fear, but then her love for Sasuke and her own determination to survive could kick in. She might try to counter - attack in a non - lethal way, hoping to subdue Sasuke rather than harm him. She could also call out to their shared memories in an attempt to stop him from actually killing her.
Sasuke might develop more patience. Since Itachi is younger in this fanfiction, Sasuke has to be more understanding. He can't be as impulsive as he usually is. For example, he might have to learn to soothe Itachi when he's scared or upset, which helps Sasuke grow into a more empathetic person.
Sasuke could also be confused. He has always had a mix of emotions towards Itachi, including love, hate, and envy. Being kidnapped by him would add another layer of confusion. He might wonder if Itachi has some new plan or if he's finally going to reveal some long - hidden truth. So, he might hold back on his full - fledged resistance and wait to see what Itachi has to say.
He might feel anger. Since he was so set on revenge against Itachi, any portrayal that didn't match his view of himself as the victor could make him angry.