Well, Negan first appears in the series as a major antagonist. He has a very distinct personality. He's confident, often to the point of being cocky. His group, the Saviors, would extort other communities for resources. He uses fear as a tool to control those around him. His actions have a huge impact on the other characters in the show, like Rick and his group.
Well, Negan's end in the comics isn't straightforwardly due to one specific killing act. It's more complicated and involves multiple factors and characters' actions.
In the online novel Lord of the Mysteries published by Qidian Chinese Network, Duke Negan was a hereditary noble of the Loen Kingdom. He belonged to the Amman family and was also the deputy director of MI9.
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