There are lots of exciting plot twists. Tanjiro's quest to turn Nezuko back to normal and his battles against powerful demons are central. Also, the reveal of the demons' origins and the organization behind them adds depth.
Well, sometimes the art style can vary. In some cases, the anime might simplify complex manga designs for better animation. Also, the pacing can be different, with the anime either speeding up or slowing down the story.
The major plot points include Takemichi's discovery of his time - leaping power. Then there's the formation and growth of Toman. There are conflicts between Toman and other gangs like Valhalla. And of course, Takemichi's quest to save Hinata which drives the whole story forward as he jumps through different timelines trying to change the events that lead to her death.
The major plot points are quite similar. The anime does a great job of bringing the manga to life without straying far. Some changes could be in the emphasis placed on certain subplots or character interactions, but they don't drastically alter the story.