One common theme is love and romance. Their relationship is often explored in depth, from the initial attraction to deeper emotional connections. Another theme could be adventure. Since they are both part of the Mass Effect universe, fanfictions might incorporate their adventures together, fighting against the Reapers or exploring new planets.
I'm not sure specifically as I haven't read it. But generally, a crossover fanfiction combines elements from two or more different fictional universes. So it might blend the concepts related to 'the kaidan effect' with the 'KOTOR' universe in some interesting ways, perhaps with new storylines, character interactions or power dynamics.
Since I haven't read 'the kaidan effect a me kotor crossover fanfiction', I can't say for sure who the main characters are. But it's likely that there will be characters from both the 'kaidan effect' side and the KOTOR side. Maybe some well - known KOTOR characters like Revan or Bastila will be involved, and there could be new characters related to the 'kaidan effect' as well.
Another way is to follow some Mass Effect fanfiction blogs. They usually curate and recommend good stories. These blogs might have reviews or summaries of the fanfictions involving female Shepard and Kaidan, which can help you decide which ones are worth reading.
One main challenge was probably her physical health. With such a high weight, she might have had trouble with basic mobility, like walking or getting out of bed.
I'm not sure specifically as I haven't read the full account. But it could be about her personal growth, her experiences in her family, or her own journey in life.
It's hard to say for sure. Some parts of the story might be based on real events, but there could also be fictional elements added for dramatic effect.