In a fanfic, Sasuke's jealousy could be related to Sakura's medical skills. Suppose Sakura starts getting requests from all over to treat important ninja. Sasuke might feel like she is being taken away from him. So, he starts acting cold towards her. Sakura notices this and decides to have a talk with him. But Sasuke being Sasuke, he doesn't open up easily. It could be a long journey of Sakura trying to break through Sasuke's jealousy - ridden shell and finally getting him to admit his love for her.
Maybe Sasuke is jealous because Sakura has achieved some great feat in the ninja world and is getting a lot of attention. In the fanfic, this could lead to Sasuke training even harder to prove himself worthy of her. Sakura, on the other hand, might be confused by Sasuke's sudden distance. She could try to reach out to him, but Sasuke's pride and jealousy keep him from being receptive. It could all come to a head during a dangerous encounter with a powerful enemy where they finally communicate their feelings.
Maybe Sakura teaches Sasuke about emotional control. Sasuke has always been brooding and angry, and Sakura, with her more empathetic nature, could show him how to manage his emotions better. This could lead to Sasuke becoming a more well - rounded ninja and a better teammate.
A plotline might involve Sakura facing a lot of judgment from the village. But she stands strong and raises the child with the help of her friends like Naruto and Ino. They support her emotionally and sometimes even materially. As for Sasuke, he might be on a journey of self - discovery and when he hears about the pregnancy, he has to decide whether his path still lies away from Konoha and his family or if he should change his ways.
One possible plotline could be that after Sasuke has finally returned to the village and reconciled with Sakura, they start to rebuild their relationship. They go on dates, share their feelings and experiences during their time apart, and gradually their love deepens until they reach a point of expressing their physical love for each other.
Perhaps Sasuke uses Sakura to get closer to some information. He might know that Sakura has connections or knowledge that can help him in his quest for revenge or for protecting the village. So he uses her in a strategic way while she is initially unaware of his motives. As the story progresses, their relationship could develop in complex ways.
The relationship could start with Sasuke being secretly jealous of Sakura's closeness to someone else. He might not show it at first, but little actions would give it away. For instance, he might glare at the other person when they are around Sakura. Sakura, being perceptive, could start to suspect something. This would create an interesting dynamic as she tries to figure out what's wrong with Sasuke.
One possible plotline could be Sasuke becoming increasingly possessive as Sakura's popularity or friendships grow. He might start to isolate her from others, thinking it's for her own good.
A possible plotline could be that Sakura discovers she has a rare and dangerous pregnancy complication. Sasuke, initially shocked, vows to protect her and find a solution. He might go on a journey to find a rare herb or seek the help of a reclusive healer. Meanwhile, Sakura is in the village, trying to stay strong and use her medical skills to keep herself and the baby alive as long as possible.
One possible plotline could be that Sasuke, feeling conflicted by his past and the secrets he holds, distances himself from Sakura and starts to develop an inappropriate emotional connection with someone else, which Sakura misinterprets as cheating. As for Itachi's role, perhaps his memories or the influence he had on Sasuke play into Sasuke's actions, like Sasuke trying to live up to some ideal Itachi had that made him question his relationship with Sakura.
One possible plotline could be that Sakura decides to raise the child on her own. She focuses on her medical ninjutsu to provide for the baby. Another could be that she tries to find Sasuke again to make him take responsibility. Maybe she faces challenges from the village as a single mother, but her friends support her through it all.
One possible plotline could be that they leave to seek a new form of power. Maybe they've discovered a threat that the Hidden Leaf isn't aware of, and they believe they can find a solution outside. Another could be that they're on a journey of self - discovery. Sakura has always been in Sasuke's shadow to some extent, and this could be her chance to truly find herself while being with him. Also, perhaps they leave due to some political unrest in Konoha that they don't want to be a part of.