With the village in general, Naruto leaving would change the dynamics. Some villagers might be relieved, thinking that the danger associated with the Jinchuriki is gone. But others, especially those who have come to know Naruto, would miss him. And for Naruto, his relationship with the village as a whole would become more complex. He would be an outsider now, but still have memories and feelings attached to Konoha, and this would be intertwined with his relationship with Sakura in the Narusaku context.
His relationships with his friends like Sasuke and Kakashi would also be affected. Sasuke might understand Naruto's decision on some level, having also left the village before. Kakashi, on the other hand, would be worried about Naruto. He might try to find him and bring him back. This could create some tension between Naruto and Kakashi as Naruto tries to assert his independence.
It could lead to political unrest in Konoha. There might be those who blame the village leadership for Naruto's departure. This could lead to power struggles as different factions try to take control and change the way the village is run. Some might demand more transparency and better treatment of their shinobi to prevent such a thing from happening again.
It could create a sense of unease and fear. Naruto is a very powerful ninja, and if he turns dark and leaves, the villagers would be worried about him coming back as an enemy. It might also lead to a decrease in morale among the ninjas who once considered Naruto a friend or ally.
His anger might cause a strain in his relationship with his friends at first. They may not understand why he is so angry and feel hurt by his sudden change in attitude. For example, Sasuke might be confused by Naruto's anger towards Konoha as he has his own complex feelings about the village.
Konoha would initially be in shock. Naruto is a hero to many in the village, and his sudden departure with Itachi, who was once considered a traitor, would cause a lot of unrest. The villagers might start to question the leadership of the village, wondering why Naruto left and if there was something they could have done to prevent it.
Sakura would be heartbroken. She has deep feelings for Naruto, and his sudden departure would make her feel abandoned. She might initially be angry at him for leaving without saying goodbye but would soon worry about his safety.
One possible plot could be that Naruto leaves Konoha due to some misunderstanding. Maybe he feels unappreciated in his relationship with Sakura (Narusaku). He might go on a journey to find himself. Along the way, he could encounter new enemies and also make new friends who help him see things from a different perspective.
On a more positive note, it could inspire some young ninja to step up. They would see Naruto's departure as a challenge to prove themselves and fill the gap he left. His leaving could also make Konoha re - evaluate its relationship with its ninja and how to keep them satisfied and in the village.
His decision could make him more self - reliant. Away from Konoha, Naruto has to depend solely on himself. He'll likely face new challenges that force him to dig deeper into his own abilities and beliefs. This could lead to a more mature and nuanced understanding of his own strength.
His friends would be worried. Sakura might be very concerned about his safety and feel sad that he left. She may also feel guilty if she thinks she could have done something to prevent his departure.
Konoha's power structure could be affected. Naruto is one of the strongest shinobi in the village. Without him, the village might be more vulnerable to attacks from other villages or threats. They would need to quickly find ways to fill the gap in their defenses.