Well, a really interesting plot twist could be that Saphira turns human but retains some dragon - like features or abilities that she has to keep secret. Maybe she has a dragon - like mark on her body that she has to conceal all the time. And also, perhaps she discovers that there are other former - dragons - turned - humans in this world, and they are all part of some sort of prophecy or a big mystery that she has to solve.
One possible plot twist could be that Saphira, as a human, has to relearn all her dragon skills in a human form. For example, she might have to find new ways to use her strength or her senses which were so much more powerful as a dragon. Another twist could be that she has to hide her true identity from other humans who might fear or try to use her if they knew she was once a dragon.
One possible plot could be that Saphira, through some magical or scientific accident, is transformed into a human. She then has to learn how to navigate the human world. She might struggle with basic human functions like eating with utensils or wearing proper clothes. At the same time, she tries to find a way to turn back into her original form, all while forming unexpected friendships with humans who are intrigued by her strange behavior and origin.
The human - turned - Nergigante discovers that they can communicate with other Nergigantes in a way no human ever could. However, they find out that the Nergigantes are planning an attack on a human settlement. This creates a moral dilemma for the transformed human. Do they side with their new kind or try to protect their former species?
Her relationship with her dragon friends would change drastically. They might not recognize her at first or might be confused about how to interact with her as a human. With humans, she would have to start from scratch in building relationships. She might initially be seen as an outcast due to her strange behavior that is influenced by her dragon nature.
Well, the plot could start with a young mechanic who is always around cars. One day, while working on a very special vintage car, there's a strange energy surge. The next thing he knows, he is the car. He experiences life from a different perspective. He can't speak in the traditional sense but tries to convey messages through his headlights and horn. He discovers he has new senses, like being able to detect mechanical problems in other cars just by being near them. He goes on a journey to find a way to turn back into a human while having many encounters with different people and cars along the way.
Maybe in the fanfiction, there's a scientific experiment gone wrong. A human scientist was trying to find a way to bridge the gap between humans and monsters. Sans, being a curious skeleton, volunteered to be a part of the experiment. However, instead of just creating a connection, the experiment transforms Sans into a human. As a human, he experiences new emotions more intensely, like hunger and fatigue, which he didn't really have as a skeleton. He then uses his new human form to try and convince other humans that monsters are not to be feared.
One possible plot could be Sonic accidentally getting hit by a strange energy beam during a battle with Dr. Eggman. This beam could have some sort of mutagenic effect that slowly starts to transform him into a human. As he turns into a human, he has to deal with the loss of his super speed at first. He then has to adapt to living as a human while still trying to protect his friends and the world from Eggman's new threats.
The plot of a Naruto turns into Sakura fanfiction could involve Naruto experiencing Sakura's emotions more directly. He might feel the pressure she has always felt to keep up with Naruto and Sasuke. This could lead to him understanding her better and trying to change things when he turns back. Also, there could be a situation where Naruto - as - Sakura has to go on a mission alone. This would force him to fully embrace Sakura's skills and personality. He could end up using her intelligence and strategic thinking in ways he never thought possible, which would not only be a growth for the 'Naruto - in - Sakura' character but also an interesting exploration of Sakura's potential.
Well, one possible plot could be that Sans discovers a mysterious magic spell or artifact that gradually transforms him into a human. As he changes, he has to deal with new sensations like feeling pain and hunger in a more intense way. He also might struggle with how other characters in the Undertale world view him now that he's different.
Well, one possible plot could be that the alien is conducting some sort of experiment on Earth. It sees humans as interesting subjects and decides to transform a human into a cow as part of its study on different species' behaviors. Maybe it wants to see how the human mind copes with being in the body of a cow, like how it interacts with other cows and its reaction to the simple life of a cow.
Well, perhaps in the fanfiction, Peter's memories as an adult are still somewhat intact in his baby form. So he tries to communicate with his loved ones in his own baby - like ways, like making specific noises when danger is near or trying to write in a very clumsy way. This could lead to some really cute and interesting interactions.