Perhaps the female symbiote starts out as a villain but then has a change of heart. She could start seeing the good in the people of New York and decide to use her powers for good. This would be a great character arc, showing her growth from a self - centered being to a hero, all while dealing with the unique powers and challenges that come with being a symbiote.
Another possibility is that the female symbiote has its own motives and goals. It could be from a different planet or dimension and is trying to find a way home while being attached to a human in the Spiderman universe. This could lead to a lot of conflict as she tries to balance her own needs with the well - being of the people around her.
One interesting storyline could be them teaming up to fight a new villain in New York. They both have unique skills, and seeing how they combine their abilities to take on the bad guy would be exciting.
One interesting storyline could be Peter Parker (Spiderman) having to balance his superhero duties with the complex relationships in his harem. For example, he might have to keep his identity secret from some of the girls in the harem while dealing with their different personalities and needs.
One interesting storyline could be Spiderman and Deadpool teaming up to take on a powerful new villain that neither could defeat alone. They'd use their unique skills, like Spiderman's web - slinging and agility and Deadpool's unorthodox fighting style and regeneration.
One interesting storyline could be Deadpool and Spider - Man teaming up to take on a powerful new villain that neither could defeat alone. They would have their comical banter while trying to figure out the villain's weakness.
There are also storylines where Spiderman's secret identity is at risk within the Avengers. Maybe a villain has found a way to infiltrate the team and is trying to expose him. This creates a lot of tension and drama as Spiderman has to protect his identity while still being part of the team.
Perhaps a storyline where X - 23 is initially distrustful of Spiderman due to his more light - hearted approach. But as they face challenges together, she comes to respect him and they form a strong bond. This could involve a lot of character development for both of them.
He might use his intelligence and knowledge of the symbiote's weaknesses. For example, if the symbiote has a weakness to high - pitched sounds, he could use some sort of sonic device to draw it out and then capture it. Or he could try to appeal to the part of the symbiote that once had a bond with him, by showing it that they were better together than apart.
Perhaps a story where they have to protect a mutual friend. Spiderman uses his scientific knowledge to figure out the bad guys' plan while Daredevil uses his street - smart instincts. They have some friendly banter along the way about how to handle the situation best, which shows their different approaches but strong friendship.
One possible storyline could be them teaming up to take on a new super - villain in the PS4 - inspired New York City. Maybe this villain has some kind of power related to the PS4 technology, like being able to control digital glitches in the real world. Spiderman's acrobatic skills combined with Black Cat's stealth would make for an exciting battle against such a foe.
In some fanfictions, there could be a story where Harry discovers Peter's secret identity in a unique way. Maybe he stumbles upon Peter changing into his Spiderman suit by accident. Then, their friendship takes a new turn as Harry has to decide whether to support Peter or be angry about the secrecy.