Perhaps a plot twist could be that in this do - over, Sasuke and Sakura actually go back in time to the moment when things started to go wrong in their relationship. They then have the chance to change the past actions that led to their separation and heartache. This would involve them having to face their younger selves and deal with all the insecurities and misunderstandings that were there from the start. It would be a very complex and emotional journey for both of them, but it could lead to a much more satisfying and healthy relationship in the end.
In this type of fanfiction, their relationship can be improved by better communication. Often in the original story, Sasuke and Sakura had misunderstandings due to lack of communication. If in the do - over, they are more open with each other, sharing their feelings and fears, it would strengthen their bond. For example, Sasuke could share his real reasons for his actions with Sakura, and she could in turn tell him how his actions affected her.
Fanfiction often takes the existing characters of Sasuke and Sakura and gives them new scenarios. In this 'do - over' concept, perhaps it's about them re - experiencing a part of their story. For example, if there was a fight or a misunderstanding in the original story, the fanfiction might have them go through it again with different reactions and outcomes. It could also be about their personal growth and how this do - over affects their individual development as characters.
One possible plot twist could be that Sakura initially rejects Sasuke. This would be a huge turn from the expected outcome as Sasuke's confession is a big deal. Maybe Sakura has her own insecurities or unresolved feelings for someone else like Naruto. Another plot twist could be that Sasuke's confession is part of a bigger plan, perhaps related to protecting Sakura from an unseen danger. He might be using his confession to keep her close and safe without truly having romantic feelings at first. Or, there could be a twist where Sakura accepts Sasuke but then they face some external force trying to break them apart, like a powerful enemy who doesn't want them to be together because their combined power could be a threat.
One possible plot twist could be that Sasuke has been under a genjutsu that makes him target Sakura, and Naruto has to break the genjutsu first to truly save her. Maybe the one who cast the genjutsu is a new, powerful enemy who wants to disrupt the bond between Team 7. Naruto, with his strong will and newfound powers, manages to find the source of the genjutsu and free Sasuke from its control, thus saving Sakura from harm.
Perhaps there could be a rival who tries to break them apart. This rival could be someone from Sasuke's past who has a grudge against him and sees Sakura as a way to get revenge. They might spread false rumors about Sasuke to make Sakura question his loyalty.
A plot twist could be that Akatsuki has a hidden agenda that Naruto, Sasuke and Sakura are unaware of when they join. Maybe Akatsuki is being controlled by an even more powerful and sinister force, and the three are lured in as pawns. They then have to figure out the real situation and fight not only against the Akatsuki members who oppose their reform ideas but also against this hidden power.
In some Sakura and Sasuke time travel fanfictions, a great plot twist is that they time travel to a point where they meet their younger selves. This can lead to some really complex and emotional situations. The younger Sasuke might not trust the future Sasuke, thinking he's an imposter or has been corrupted. The same could go for Sakura. Another plot twist could be that the time travel is caused by a forbidden jutsu that Sakura accidentally activates. And as they travel through time, they start to lose their memories bit by bit, adding a sense of urgency to their journey to get back to their own time and figure out what's going on.
A plot twist could be that Sarada discovers she has a hidden power that neither Sasuke nor Sakura are aware of. It could be related to a long - lost Uchiha ability that skipped generations.
A great plot twist could be that Sasuke suddenly loses his sharingan and has to rely on his other skills and the help of the others. Naruto might have to train Sasuke all over again, and Hinata and Sakura could be involved in finding a way to restore Sasuke's sharingan. It would change the dynamics of their relationships and how they interact with each other.
Another plot twist might be that Sasuke discovers a hidden enemy who is targeting their unborn child. This could lead to Sasuke having to go on a dangerous mission while Sakura is pregnant to protect their family. It would add a lot of tension to the story as Sakura is left at home worried about him.