Sakura would likely be a main character as well. She could be the love interest for Naruto or Sasuke. Her intelligence and strength in the original series would translate well into a school setting, perhaps as the top student in some subjects or a leader in a school club.
Sasuke could also be a main character. His cool and aloof demeanor would contrast with Naruto's more exuberant personality. There could be a lot of interesting interactions between them, like competing in school competitions or arguing over different ideas in class.
Perhaps it would focus on the relationships in school. Naruto could have a crush on Sakura and try to impress her during school days. There might be love triangles or friendly rivalries among the characters, adding drama to the fanfic. The story could also show how they grow and learn from each other in the school environment.
Obviously Naruto has to be one of the main characters. He'd be the energetic and sometimes clumsy student who is always getting into trouble but has a heart of gold. Sakura would also be a main character, the smart and strong - willed girl who is often exasperated with Naruto's antics. And Sasuke, the cool and aloof student who has a mysterious past and is the object of many students' admiration.
It could be two best friends. They decide to go on a spontaneous road trip for one night and two days. They share stories, laugh, and have a bit of an argument when one wants to take a different route. But in the end, they come out stronger as friends.
It could be a rogue ninja who has a personal vendetta against Naruto. Maybe someone from his past that he thought was defeated but has come back stronger after a hundred days of secret training in some dark arts.
Teachers might also be main characters in some ways. They guide the students, for instance, a very strict but fair teacher who has a big influence on the students' growth. There could also be the class clown type of student who always brings laughter to everyone around.
The main character could be a young trainer named Ash. He's always eager to learn more about Pokemon and is very friendly. Another character could be Misty, a girl who is really good with water - type Pokemon and is a bit of a tomboy. There could also be Brock, who is knowledgeable about Pokemon care and often gives advice to other students.
Naruto himself could be the main character. He's the most well - known in the Naruto series. His energetic and determined personality would make for an interesting story in a school setting with god - like powers. He could be the one who unites the other students against any threats in the school.
In high school in this fanfic, Naruto would likely be known for his pranks. Hinata, on the other hand, would be the quiet and studious one. Their relationship could start with small exchanges, like Naruto borrowing a pencil from Hinata in class. He might not think much of it at first, but Hinata would be so nervous. As time goes on, Naruto might start to see Hinata in a different light, especially when she stands up for him against some bullies. This could be the start of a sweet high school romance.
I think Tsunade could be a main character in a 'naruto himekishi fanfic'. Given her strength and leadership, she could be in charge of the himekishi in the Hidden Leaf Village. Another possible main character could be Rock Lee. His hard - working and determined nature would fit well with the concept of the himekishi. And of course, Sasuke could also be involved. Maybe he has a complex relationship with the himekishi, either as an ally or an antagonist depending on the story's direction.
Obviously, Naruto could be one of the main characters. He could be either a patient or someone helping out at the hospital. Another main character could be Sakura. Since she has medical skills, she could be a doctor or a medic - ninja in charge at the hospital. And then there could be a new character, like a young orphan who is being trained as a medic - ninja at the hospital and has an interesting backstory.