Well, a plot could revolve around Orochimaru and Sasuke going on a journey to find a rare ingredient for a powerful elixir. Along the way, they encounter different enemies and allies from the Naruto universe. They might also have to face their own inner demons during this journey. For example, Sasuke has to deal with his lingering hatred while Orochimaru has to confront his thirst for power in a new way.
Perhaps a plot where Orochimaru and Sasuke are forced to team up to stop a greater evil that is threatening the entire ninja world. This evil could be a powerful and ancient being that neither of them could defeat alone. As they fight together, they start to understand each other better. Sasuke might learn from Orochimaru's vast knowledge of ninjutsu, and Orochimaru could gain a new perspective on loyalty and friendship from Sasuke.
A possible plot is that Orochimaru, in his exile, stumbles upon a powerful artifact that could change the balance of power in the ninja world. Anko, suspecting his motives, follows him. As they both reach for the artifact, they are transported to a different dimension. There, they have to rely on each other to find a way back. During this time, they learn more about each other's true natures. Another idea is that Anko is given a mission to spy on Orochimaru's new lair. But instead of finding something evil, she discovers that he is secretly protecting a group of innocent people. This revelation makes her see him in a new light and they start to form an alliance.
Well, perhaps there could be a plot where they both get trapped in a mysterious dimension. In this dimension, they have to rely on each other's skills. Jiraiya's knowledge of sage mode and Orochimaru's various jutsu could be combined to find a way out. It could also explore their relationship in a more in - depth way as they face different challenges together.
Perhaps Orochimaru sees Sakura as a key to unlocking some ancient jutsu. He has discovered that her chakra has a unique property that could be the missing link. So he starts to stalk her, leaving her little clues about what he wants. Sakura initially has no idea what's going on until she starts to piece things together and realizes she has to protect herself and her friends from Orochimaru's plans.
One plot idea could be Sakura exploring her unique abilities inherited from Orochimaru while trying to distance herself from his dark reputation. Maybe she discovers a new form of jutsu that combines Orochimaru's snake - based techniques with her own medical ninjutsu skills.
Maybe in the fanfiction, Naruto gets trapped in one of Orochimaru's old experiments. Female Orochimaru, out of curiosity about Naruto's power and his unique personality, decides to study him up close. But during this time, Naruto manages to show her the value of human connection and kindness, which she has long forgotten, leading to a deep bond between them.
One idea could be Orochimaru as a girl struggling to gain respect in the male - dominated ninja world. She might have to prove herself even more than her male counterparts. For example, she could be constantly underestimated in battles or when trying to learn advanced jutsu. Another plot could involve her using her femininity in unique ways to deceive her enemies. Maybe she pretends to be a damsel in distress only to turn the tables on them.
One plot idea could be Orochimaru seeing some potential in child Naruto that is different from the Nine - Tails. Maybe he wants to train Naruto in a different form of jutsu, not for evil but for some self - serving yet not completely malicious purpose. For example, he could be interested in Naruto's ability to make friends and wants to use that to his advantage in the ninja world.
One idea could be a story where Kushina and Orochimaru are forced to team up in a mission. They initially dislike each other due to their different natures. Kushina, being warm - hearted and Orochimaru, being more self - interested. But as they face challenges together, they start to understand and respect each other's abilities.
One interesting plot idea could be a story where a young shinobi is secretly sent into Orochimaru's lab as a spy. They discover new, forbidden jutsu experiments that Orochimaru is conducting on captured ninja. Another could be about a group of Orochimaru's former test subjects who team up to destroy the lab and all its secrets. And a third idea is a story where Orochimaru's lab holds the key to curing a mysterious illness that is spreading across the ninja world.
One idea could be Orochimaru taking an unexpected interest in Naruto's growth not for his power but for his unique way of seeing the ninja world. Maybe Orochimaru starts to secretly guide Naruto in some unorthodox ways of chakra control, which Naruto initially resists but later realizes could be useful.