The main villains in the Cosmic Spider - Man story are quite interesting. Firstly, there's Mysterio. In this story, he uses his illusions in a more cosmic - level way to deceive Spider - Man. He teams up with some other villains to try and bring down Spider - Man. Then there's Sandman, who has been corrupted by a cosmic force and is now a more menacing foe. Another big villain is Carnage. He has a new form that is powered by a dark cosmic energy. All of these villains pose different threats to Spider - Man and his new cosmic - powered self.
The Green Goblin is a main one. He's always causing trouble for Spider - Man. Norman Osborn, as the Green Goblin, has a complex relationship with Peter Parker, which makes their battles even more interesting.
Some of the main villains in Insomniac Spider - Man 2 are Kraven the Hunter and Venom. Kraven is a formidable foe known for his hunting skills, and Venom brings his own unique set of challenges with his symbiotic powers.
Venom is another important villain. He has a symbiotic relationship with an alien entity. This gives him enhanced strength and abilities, and his hatred for Spider - Man makes for some intense battles in the graphic novels.
Green Goblin is very memorable. His crazy laugh and the flying glider make him stand out. He has a complex relationship with Spider Man as Norman Osborn is also connected to Peter's personal life.
Well, the Kingpin could be a main villain. He could see Naruto as a threat to his criminal empire in New York. He might hire some ninja mercenaries from the Naruto universe to take him down. And then there's Electro, who could be enhanced by some sort of chakra - based technology. He could use his new powers to cause chaos in the city and target Naruto specifically, thinking that he's the key to getting even more power.
The Green Goblin is very memorable. His maniacal laughter and his crazy stunts on the glider, along with his complex relationship with Spider - Man, make him stand out. He was one of the first major villains and set a high bar for the others.
One possible villain could be Doctor Octopus. He might be back with some new and improved mechanical arms, and he wants to prove that he's the superior scientist and villain by defeating both Spider Man and Spider Girl.
The Green Goblin is very popular. His chaotic nature and personal vendetta against Spider - Man make for great storytelling in fanfiction.
Aldrich Killian is another villain. He creates the Extremis virus and uses it for his own malicious purposes. He tries to get revenge on Tony Stark and cause chaos with his new - found power.
There's also Justin Hammer. He's a rival to Tony Stark in the business world. He's jealous of Stark's success and teams up with other villains to try and bring him down. He's not as physically powerful as the others but is quite devious in his plots against Iron Man.