Well, a cool plot twist could be that Neji - as - a - girl discovers new jutsu or abilities that were hidden because she was male before. This could completely change her role in the ninja world. Also, there could be a plot twist where the enemies of the village target her specifically because of her new - found femininity, thinking she's a weaker target. But in reality, she uses this misperception to her advantage and defeats them in unexpected ways.
One possible plot twist could be that Neji, as a girl, has to face different challenges in the ninja world. For example, she might initially struggle with the new physical limitations or advantages that come with being female in a male - dominated ninja society. Maybe she has to deal with different expectations from her clan and friends, which could lead to some interesting character development. Another plot twist could be in her relationships. Her former male friends might start to see her in a new light, leading to some complicated romantic or platonic dynamics.
Well, a possible plot twist could be related to Sasuke's family. Maybe when he turns into a girl, he discovers some long - hidden secrets about his family that were only accessible in this new form. Also, in the ninja world, being a female Sasuke could lead to different political implications. The other villages might view him/her differently and try to use this transformation to their advantage. It could also be a twist if Sasuke, as a girl, has to fight against gender stereotypes within the ninja community.
One possible plot twist could be that Kakashi, as a girl, has to deal with different social expectations in the ninja world. For example, she might face more restrictions in combat training because of her new gender. Another could be that she uses her new form to her advantage in undercover missions, fooling enemies who are less likely to suspect a female. Also, there could be a romantic plot twist where a character who previously saw Kakashi as a rival now has different feelings for her as a girl.
One possible plot twist could be that Orochimaru turns Naruto into a girl as part of a grand experiment. But Naruto, now a girl, still has his (or rather her) strong will and uses this new form to infiltrate an all - female group that Orochimaru wants to target. This way, Naruto can gather intelligence and thwart Orochimaru's plans from the inside.
Well, a really interesting plot twist could be that the transformation into a little girl is part of a genjutsu cast by a powerful enemy. But while in this form, Naruto discovers new aspects of the ninja world that are usually hidden from male ninjas. Maybe there are secret female - only ninja techniques she stumbles upon and has to master to break the genjutsu.
A plot twist could be that Orochimaru's transformation into a girl is part of a larger, more complex jutsu that was set in motion long ago. In this new form, she has access to different types of chakra or abilities that she didn't have before. This makes her a target for other villains who want to use her new powers for their own gain, and Naruto has to protect her while also being cautious of her true intentions.
One possible plot twist could be that Neji has to go on a dangerous mission right before the wedding. It would put their relationship to the test as Tenten would be worried sick about him. Another twist could be that there's a misunderstanding within their families regarding some old traditions that might affect the marriage. For example, an old family feud resurfaces that threatens to stop the wedding. And a third plot twist could be that Neji loses his memory due to a jutsu gone wrong just days before the wedding, and Tenten has to make him fall in love with her all over again.
One possible plot twist could be that they initially thought the pregnancy was normal but then discover it's a very special and rare kind of pregnancy in their ninja world. Maybe it has some connection to a long - lost jutsu or a prophecy.
One possible plot twist could be that the TMNT turn into dragons not because of some magic spell gone wrong, but because it's an ancient prophecy. They are the only ones who can save the city in their dragon forms from a powerful, otherworldly threat. As dragons, they have new powers like breathing fire or flying at supersonic speeds, which they use to fight the enemy.
Maybe there's a plot twist where Sakura discovers that Neji was forced into the arranged marriage against his will. This could lead to her trying to find a way to break the arrangement in a way that doesn't cause too much trouble for their families or clans. However, in the process, they start to develop real feelings for each other.
One interesting plot twist could be that Neji discovers a new power within his Byakugan that makes him evenly matched with Naruto's Nine - Tails power. Maybe he unlocks a hidden ability that allows him to see through Naruto's chakra cloaks or disrupt the Nine - Tails' chakra flow. Another plot twist could be that Naruto loses his access to the Nine - Tails' chakra during the fight, and has to rely solely on his own skills and training, making it a much more even match against Neji.