Perhaps a plot where Sakura is on a quest to understand the secrets of the Akatsuki, and she approaches Kisame as he seems like the most approachable member at first. But Kisame has his own motives and initially tries to mislead her. However, as they interact more, they both find themselves in a situation where they need to rely on each other to survive against a common enemy, like a powerful rogue ninja.
One idea could be a story where Kisame and Sakura are forced to team up during a mission in a strange, new land. They start off distrusting each other but gradually learn to respect one another's skills. For example, Kisame is impressed by Sakura's medical ninjutsu when she heals him from a near - fatal wound. Another plot could be set in an alternate universe where they are both students at the ninja academy together, and their different personalities lead to some comical and also some heartfelt moments as they grow up.
A plot could also revolve around Kisame and Sakura being trapped in a genjutsu - created world. In this world, they have to work together to break free. Along the way, they discover things about each other that they never knew before. For instance, Sakura might learn about Kisame's past and the reasons he joined the Akatsuki, which makes her see him in a new light, and Kisame might see Sakura not just as a Konoha ninja but as an individual with great determination and a kind heart.
A really interesting plot could be a time - travel fanfiction. Suppose Sakura somehow travels back in time and meets a younger Kisame. She tries to change his path, knowing the future he will have. This could involve a lot of complex character development as Sakura has to deal with the differences in their values and the knowledge she has of his future actions.
One plot idea could be a story where Kisame and Itachi are on a mission together in a mysterious land. They encounter various challenges that test their loyalty to each other and their organization. As they face these difficulties, they start to understand each other on a deeper level, sharing their past traumas and dreams. This could build a strong bond between them without any inappropriate content, focusing more on their friendship and mutual respect.
Well, a plot could involve Kisame's sister being a healer. Naruto gets seriously injured in a battle and she is the only one who can save him. As she heals him, they start to share their stories and dreams. This leads to her realizing that the Akatsuki's ways might not be right. Also, she could be in a love triangle between Naruto and a member of the Akatsuki, which would add a lot of drama to the story. There could also be a plot where she discovers a prophecy that Naruto is the key to saving the ninja world, and she decides to protect him at all costs.
One interesting plot could be that Naruto discovers a hidden power within Kisame's sword. Maybe during a battle, the sword starts to react to Naruto's chakra in an unexpected way, leading to a new form of combat for Naruto.
Another plot could revolve around Itachi and Kisame having a philosophical debate during a long journey. Since Itachi has his own complex moral code and Kisame is more straightforward in his loyalty to the Akatsuki, they could discuss the meaning of loyalty, power, and the end goals of their organization. This could lead to a deeper understanding between them or even a rift, depending on how the story unfolds.
One possible plot could be that Sakura, on a mission in a far - off land, encounters Kisame. At first, they are enemies as Kisame is from the Akatsuki and Sakura is a Konoha ninja. But then, they find themselves in a situation where they have to work together to survive against a greater threat, like a powerful ancient beast. As they fight side by side, they start to understand each other's motives and pasts, and Sakura begins to see that Kisame is not just a mindless villain.
One possible plot could be that Sakura, known for her intelligence and determination, meets Kisame, the imposing figure. Maybe they end up in the same study group. Sakura is initially wary of Kisame because of his tough exterior. But as they work together, they discover each other's hidden sides. For example, Kisame might have a love for art that Sakura stumbles upon, and she starts to see him in a new light.
A plot could involve Sakura being targeted by an enemy who wants to use her medical knowledge for evil purposes. Shisui, being a skilled ninja, decides to protect her. As they go on the run together, they start to understand each other better. Shisui might teach Sakura some unique ninja techniques, and Sakura could help Shisui deal with his own emotional traumas. Another idea is that they both get involved in a mystery within the Hidden Leaf Village. There are strange disappearances, and they suspect that there is a powerful enemy at work. They have to use their combined skills, Sakura's intelligence and medical expertise and Shisui's combat and Sharingan abilities, to solve the mystery.
One plot idea could be that Gaara and Sakura are on a joint mission in a foreign land. They have to rely on each other's skills. Gaara's sand control and Sakura's medical ninjutsu and brute strength can complement each other. For example, Sakura gets injured while fighting off some powerful enemies, and Gaara uses his sand to protect her until she can heal herself. Then they continue the mission together and form a deep friendship along the way.
A third plot idea is that Madara is somehow cursed and Sakura, with her medical and combat skills, is the only one who can help him. In the process, they start to understand each other better. Madara discovers that there is more to the younger generation than he thought, and Sakura realizes that there is a depth to Madara that goes beyond his villainous reputation.