The plot and ending of the ghoul anime version and the manga version were different. The storyline and character settings of the anime and manga version were different. The animated version set the story in a fictional world while the comic version took place in the real world. In the anime version, the ghouls were mutated from humans, but in the comic version, they were mutated from viruses. In the manga version, the ghouls had been sufficiently controlled and spread across the globe. In the end, human society faced an unprecedented crisis, and the protagonists had to do their best to prevent this disaster from happening. As for the ending, the manga version of the ghoul was still in the midst of being serialised. There was no clear ending yet. However, according to some readers, the ending of the comic version might involve the final battle between humans and ghouls, as well as the future plans of this world.