Zhou Zuoren's literary creation occupied an important position in the history of literature. His works covered novels, essays, poems and many other fields. His unique style and profound thoughts had a profound impact on modern Chinese literature. Zhou Zuoren's novels were famous for their realistic, in-depth, and meticulous descriptions of social life, such as A Madman's Diary, The True Story of Ah Q, and The Kingdom of Wine. These works revealed the various problems of Chinese society and explored the profound philosophical issues of human nature, freedom, and democracy, which had an important impact on the development of modern Chinese literature. Zhou Zuoren's prose works were famous for their unique thoughts and literary style, such as "Part","Reality and Emptiness","Solitude and Pursuit" and so on. Zhou Zuoren's prose style is concise and bright, focusing on the unity of ideology and artistry. His profound ideology and unique literary style have become one of the pioneers of modern Chinese prose. Zhou Zuoren's poems also had high artistic value, such as "The Song Girl of the End of the World" and "The Goose Returning". Zhou Zuoren's poetry style was varied and full of romanticism. The deep thinking about life, society and nature in his works also had an important impact on the development of modern Chinese poetry. To sum up, Zhou Zuoren's literary creation has an important position in the history of literature. His works reveal the problems of modern Chinese society and explore profound philosophical issues such as human nature, freedom, and democracy, which have a profound impact on the development of modern Chinese literature.