It was difficult to have a definite answer to this question because many tragic female protagonists in literature had their own unique stories and experiences. Here are the names of some of the most tragic female protagonists in famous literature: - Lin Daiyu from 'Dream of the Red Chamber'. She was a beautiful and intelligent girl who had experienced the decline of her family, emotional entanglements, and the misfortune of her life. - Wu Song from Water Margins. He was a hero, but he was also a man who suffered injustice, losing his family and freedom. - The king of the Kingdom of Women in Journey to the West. She was a beautiful and intelligent woman, but because of her identity and her husband's betrayal, she suffered endless suffering and torture. - Diao Chan from Romance of the Three Kingdoms. She was a beautiful, intelligent and ambitious woman, but she was also teased by fate and eventually became Dong Zhuo's lover and suffered torture. - It was Jean Valen from 'Miserable'. He was a poor, kind tramp who eventually lost his life because of the revenge of others. Although these characters suffered different misfortunes, they all expressed the injustice of fate and the struggle of human nature, becoming one of the tragic female protagonists in classic literary works.