The list of most popular mystery novels may vary according to different reader groups and regions, but the following are some of the most popular mystery novels around the world that may have received widespread praise and readers 'love: Sherlock Holmes (Arthur Conan Doyle) 2 Agatha Christie 3. Calvino (Karloff) 4. Hirohito Keigo 5 Michelangelo Antonio Da Vinci 6. Raymond Chandler 7 Philip K Dick 8 Edgar Allan Poe 9 Karl Brangel 10 Margaret Atwood (Margaret Atwood) It is important to note that this ranking is not static because readers 'tastes and preferences are constantly changing. In addition, there were many other excellent detective novels such as Morpassant, Ernest, Margaret Atwood, etc. They were also highly respected around the world.